Plankton comprises a large diversity of organisms, from pico- to macro-sized classes, and spans several trophic levels, whose population dynamics are characterized by a high spatio-temporal variability.Studies integrating multiple plankton groups, in respect to size classes and trophic levels, are still rare, which hampers a more thorough descripti
Titanium Dioxide Nanomaterials: Progress in Synthesis and Application in Drug Delivery
Background: Recent developments in nanotechnology have provided efficient and promising methods for the treatment of diseases to achieve better therapeutic results and lower side effects.Titanium dioxide (TiO2) nanomaterials are emerging inorganic nanomaterials with excellent properties such as low toxicity and easy functionalization.TiO2 with spec
The Spiral Discovery Network as an Automated General-Purpose Optimization Tool
The Spiral Discovery Method (SDM) was originally proposed as a cognitive artifact for dealing with black-box models that are dependent on multiple inputs with nonlinear and/or multiplicative interaction effects.Besides directly helping to read more identify functional patterns in such systems, SDM also simplifies their control through its character
The role of stereotactic radiotherapy in the treatment of the local recurrence of colorectal cancer: A case report
Colorectal cancer is one of the most common malignant diseases worldwide.A multidisciplinary approach to treatment involves surgery and chemotherapy, while radiotherapy is used in the treatment of tumors localized in the pelvis.Stereotactic radiotherapy allows the delivery of high, ablative radical radiotherapy doses to target volumes, with a reduc
Amino acid deprivation triggers a novel GCN2-independent response leading to the transcriptional reactivation of non-native DNA sequences.
In a variety of species, reduced food intake, and in particular protein or amino acid (AA) restriction, extends lifespan and healthspan.However, the underlying epigenetic and/or transcriptional mechanisms are largely unknown, and dissection of specific pathways in cultured cells may contribute to filling this gap.We have previously shown that, in m